Hormesis: 3 Science-Backed Ways to Train Your Stress Response

Hormesis: 3 Science-Backed Ways to Train Your Stress Response

Our bodies and brain thrive on short-term acute “stress” exposure by ramping up growth and repair. Here are three science-backed ways to increase resilience with hormesis.

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Qualia Immune - The Science Behind The Formula & Immune System Intelligence

Qualia Immune - The Science Behind The Formula & Immune System Intelligence

Qualia Immune combines 19 carefully selected ingredients for premium immune support. We think of it as being training for the immune system; a formulation designed to challenge the immune system in ways that will help it be fitter and perform more intelligently. 

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Qualia Senolytic Pilot Study

Qualia Senolytic Pilot Study

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Can We Change the Future of Disease Prevention by Decoding Our Biology? - An Interview With Dr. Momo Vuyisich

Can We Change the Future of Disease Prevention by Decoding Our Biology? - An Interview With Dr. Momo Vuyisich

Is science on the cusp of changing the future of disease prevention via  a deeper understanding of an individual’s biology at a molecular level?

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The Formulator's View of the Qualia Senolytic Ingredients

The Formulator's View of the Qualia Senolytic Ingredients

What is Qualia Senolytic? It is a dietary supplement formulated to help bring the creation and removal of senescent cells back into a healthy balance. Here's a deep dive into the ingredients included in the formulation.

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Anti-Aging Benefits of Intermittent Fasting

Anti-Aging Benefits of Intermittent Fasting

In Silicon Valley, the hub of anti-aging research and funding, countless entrepreneurs and high-profile celebrities use fasting to combat the effects of aging. In Anti-Aging Benefits of Fasting, we will explore the mechanisms that create these fasting benefits. This part is more scientific than the others, but we emphasize only crucial components in an easily digestible format.

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NAD: Introduction to an Important Healthspan Molecule

NAD: Introduction to an Important Healthspan Molecule

In this article we’ll be covering the “big picture” when it comes to NAD. We’ll be doing a deeper dive on specific topics we introduce in this article in subsequent articles in this series. As you go through this series of articles please keep in mind that, like other molecules in the body, NAD+ is a means to an end. We don’t care about NAD+ on its own; we care about it because of what it allows cells to do. 

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The 9 Hallmarks of Aging

The 9 Hallmarks of Aging

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Mitochondria Health: An Exploration of Temperature and Light Therapy

Mitochondria Health: An Exploration of Temperature and Light Therapy

Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. Here we explore temperature and light therapy to improve mitochondrial health and support healthy aging.

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 How is NAD+ Made? Preiss-Handler Pathway

How is NAD+ Made? Preiss-Handler Pathway

In 1958, Jack Preiss and Philip Handler published a scientific paper describing how NAD+ was made from niacin in three steps.(1) This pathway was later named the Preiss-Handler pathway after the co-discoverers. It describes the enzyme steps needed to convert niacin into the NAD+ molecule.

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NAD+ Consumption Uses: An Overview

NAD+ Consumption Uses: An Overview

The NAD+ form of the molecule is required for certain cellular signaling reactions that change the way cells behave. Unlike redox, where the molecule is conserved, the NAD+ molecule is broken apart or “consumed” when used for signaling. It’s these NAD+ consumption uses that have been a main reason for the resurgence of scientific interest in strategies to boost NAD+.

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How is NAD+ Made? Salvage Pathway

How is NAD+ Made? Salvage Pathway

The salvage pathway is used to produce NAD+ from nicotinamide molecules. Whether the source of the nicotinamide is vitamin B3 (as niacinamide), newer nicotinamides (e.g., nicotinamide riboside [NR], nicotinamide mononucleotide [NMN]), or molecules in food that get broken down during digestion into nicotinamide, the salvage pathway turns them into NAD+ in our tissues.

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How is NAD+ Made? De Novo Synthesis

How is NAD+ Made? De Novo Synthesis

Most organisms have several alternatives for producing the NAD+ molecule. In humans, there are three major NAD+ biosynthesis pathways: the De Novo Pathway, starting from the essential amino acid L-tryptophan; the Preiss-Handler pathway, using niacin (nicotinic acid); and the Salvage Pathway from niacinamide (nicotinamide). In this article, we’ll be covering the De Novo Pathway.

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Mitochondria: Exploring 5 Lifestyle Habits to Benefit Cell Health

Mitochondria: Exploring 5 Lifestyle Habits to Benefit Cell Health

Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. In this article, we explore lifestyle habits that improve mitochondrial health and support healthy aging.

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Qualia Life: Putting the Healthy Aging Puzzle Together

Qualia Life: Putting the Healthy Aging Puzzle Together

We all age. But, we don’t all age at the same rate. From a bottom-up point of view, we are a complex colony of tens of trillions of individual cells. We care about what healthier cells allows the body to do better. Qualia Life is our solution to cell support for better aging. 

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Why Algae is a Powerful Longevity and Detox Hack - A Q+A With the Founder of ENERGYbits

Why Algae is a Powerful Longevity and Detox Hack - A Q+A With the Founder of ENERGYbits

As Neurohackers, longevity, in relation to both lifespan and healthspan, is a topic of great interest to us. Scientific understanding in these areas is advancing rapidly as are studies linking algae to longevity.

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The Ultimate “Light Diet” to Boost Mitochondrial and Vision Health

The Ultimate “Light Diet” to Boost Mitochondrial and Vision Health

Matt Maruca, CEO of Ra Optics, shares with us 8 steps to optimizing, both mitochondrial and vision health through the power of light

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Neglected Areas of Research: What Study Would You Have Done with Unlimited Resources?

Neglected Areas of Research: What Study Would You Have Done with Unlimited Resources?

To improve our healthcare we need important research that is not being done. Often times health topics aren't studied due to lack of funds and resources. We’ve been asking our podcast guests where the missing research is in the field they are experts in. Read on to find out what they said.

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What is Mitochondrial Biogenesis? Benefits & Effects

What is Mitochondrial Biogenesis? Benefits & Effects

Similar to many other cellular processes, the creation of new mitochondria (a process called mitochondrial biogenesis), and the interacting pathways that influence it, suffers with aging. This is the bad news. The good news is that there are things we can do to better support maintaining a fitter mitochondrial network.

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Mitohormesis: How Mitochondria Protect Themselves from Oxidative Stress

Mitohormesis: How Mitochondria Protect Themselves from Oxidative Stress

In this article, we’re going to learn about mitohormesis, the activity of reactive oxygen species (ROS) as signaling molecules, and how and why ROS can be both beneficial and harmful. We will also discuss what leads to excessive ROS production and accumulation, how this associates with aging, and where antioxidants fit into the equation. Lastly, we’ll discuss nutritional strategies that can support the antioxidant defenses cells and mitochondria use to protect themselves against excessive ROS.

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What is Glycolysis? Where Glycolysis Takes Place, Definition, and Steps of the Glycolysis Pathway.

What is Glycolysis? Where Glycolysis Takes Place, Definition, and Steps of the Glycolysis Pathway.

Glycolysis is the metabolic pathway that breaks down the carbohydrate glucose to produce cell energy in the form of ATP. Glycolysis generates ATP directly, as a product of the pathway’s chemical reactions, and indirectly, using energy generated by electrons extracted from the chemical bonds of glucose. In the human body, glucose is the preferred fuel for the vast majority of cells.

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Neurohacker’s Guide to Hand Washing as an Antiviral Strategy

Neurohacker’s Guide to Hand Washing as an Antiviral Strategy

One of the public health goals of prevention is “flattening the epidemic curve*,” which essentially means decreasing the growth of new infections now, so they can be spread out over time. This is the reason why businesses are asking employees to work from home and governments are enacting policies to support social distancing strategies. In essence, public health wants to push some of the infections that might otherwise occur in the next weeks to sometime in the future … the further into the future the better.

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Can Gargling Prevent Upper Respiratory Tract Infections?

Can Gargling Prevent Upper Respiratory Tract Infections?

There’s no data suggesting that gargling prevents infection from the virus causing COVID-19. The SARS-CoV-2 virus is too new to know. But, in general, gargling might have modest preventive benefit for colds (and likely less so for the flu). Once someone has an upper respiratory infection, gargling is not a treatment for the infection. It would, at best, offer some degree of soothing of sore throat symptoms.

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Will Wearing Glasses Offer Any Protection Against Respiratory Viruses?

Will Wearing Glasses Offer Any Protection Against Respiratory Viruses?

A recent article in the New York Post suggested that wearing glasses might offer some degree of protection against respiratory viruses. We’ve also read in quite a few places comments about wearing eye protection as a possible respiratory virus prevention suggestion. Is it likely to work?

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How Does the Immune System Work? Part 1: An Exploration of the Functions, Responses, and Processes of the Innate Immune System

How Does the Immune System Work? Part 1: An Exploration of the Functions, Responses, and Processes of the Innate Immune System

The immune system is the collection of cells, tissues, and molecules that work together to recognize the healthy cells that make up the body, and protect us against the unfamiliar or damaged. 

The immune system monitors our body continuously searching for certain categories of things that may threaten our health: infectious microbes, viruses, fungi, and parasites (i.e., germs or pathogens); toxic cellular products; and damaged or diseased cells, including senescent or tumor cells.

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