The Formulator's View of the Qualia Senolytic Ingredients

The Formulator's View of the Qualia Senolytic Ingredients

What is Qualia Senolytic? It is a dietary supplement formulated to help bring the creation and removal of senescent cells back into a healthy balance. Here's a deep dive into the ingredients included in the formulation.

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Why Does Mitochondrial Health Affect Aging? 4 Science-Backed Ways to Rejuvenate Mitochondria

Why Does Mitochondrial Health Affect Aging? 4 Science-Backed Ways to Rejuvenate Mitochondria

Selectively eliminating dysfunctional mitochondria (mitophagy) and replacing them with new mitochondria (mitochondrial biogenesis) helps us stay biologically younger. But what exactly are the functions of mitochondria and how does mitochondrial health affect aging?

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Can We Change the Future of Disease Prevention by Decoding Our Biology? - An Interview With Dr. Momo Vuyisich

Can We Change the Future of Disease Prevention by Decoding Our Biology? - An Interview With Dr. Momo Vuyisich

Is science on the cusp of changing the future of disease prevention via  a deeper understanding of an individual’s biology at a molecular level?

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Anti-Aging Benefits of Intermittent Fasting

Anti-Aging Benefits of Intermittent Fasting

In Silicon Valley, the hub of anti-aging research and funding, countless entrepreneurs and high-profile celebrities use fasting to combat the effects of aging. In Anti-Aging Benefits of Fasting, we will explore the mechanisms that create these fasting benefits. This part is more scientific than the others, but we emphasize only crucial components in an easily digestible format.

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NAD: Introduction to an Important Healthspan Molecule

NAD: Introduction to an Important Healthspan Molecule

In this article we’ll be covering the “big picture” when it comes to NAD. We’ll be doing a deeper dive on specific topics we introduce in this article in subsequent articles in this series. As you go through this series of articles please keep in mind that, like other molecules in the body, NAD+ is a means to an end. We don’t care about NAD+ on its own; we care about it because of what it allows cells to do. 

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 How is NAD+ Made? Preiss-Handler Pathway

How is NAD+ Made? Preiss-Handler Pathway

In 1958, Jack Preiss and Philip Handler published a scientific paper describing how NAD+ was made from niacin in three steps.(1) This pathway was later named the Preiss-Handler pathway after the co-discoverers. It describes the enzyme steps needed to convert niacin into the NAD+ molecule.

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Will Wearing Glasses Offer Any Protection Against Respiratory Viruses?

Will Wearing Glasses Offer Any Protection Against Respiratory Viruses?

A recent article in the New York Post suggested that wearing glasses might offer some degree of protection against respiratory viruses. We’ve also read in quite a few places comments about wearing eye protection as a possible respiratory virus prevention suggestion. Is it likely to work?

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Mitochondria Health: An Exploration of Temperature and Light Therapy

Mitochondria Health: An Exploration of Temperature and Light Therapy

Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. Here we explore temperature and light therapy to improve mitochondrial health and support healthy aging.

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NAD+ Consumption Uses: An Overview

NAD+ Consumption Uses: An Overview

The NAD+ form of the molecule is required for certain cellular signaling reactions that change the way cells behave. Unlike redox, where the molecule is conserved, the NAD+ molecule is broken apart or “consumed” when used for signaling. It’s these NAD+ consumption uses that have been a main reason for the resurgence of scientific interest in strategies to boost NAD+.

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Hormesis: 3 Science-Backed Ways to Train Your Stress Response

Hormesis: 3 Science-Backed Ways to Train Your Stress Response

Our bodies and brain thrive on short-term acute “stress” exposure by ramping up growth and repair. Here are three science-backed ways to increase resilience with hormesis.

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How Metabolism Supports Immunity

How Metabolism Supports Immunity

Immunometabolism is the crosstalk between metabolic and immunological processes. Mitochondria, the cellular structures that generate cell energy, are key elements in the crosstalk between metabolic and immune signaling pathways. 

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The Ultimate “Light Diet” to Boost Mitochondrial and Vision Health

The Ultimate “Light Diet” to Boost Mitochondrial and Vision Health

Matt Maruca, CEO of Ra Optics, shares with us 8 steps to optimizing, both mitochondrial and vision health through the power of light

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What is CD38? An Exploration of NAD+ Consumption Uses and Functions of CD38

What is CD38? An Exploration of NAD+ Consumption Uses and Functions of CD38

In this article, we’re going to introduce an indirect way of supporting NAD+. Rather than making more, this article will be teaching you about using less. Using less requires downregulating a protein called cluster of differentiation 38 (CD38 for short). When CD38 is not as active, less NAD+ is used by it. The result is higher NAD+ levels and greater NAD+ availability for important healthy aging uses.

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How The Gut Microbiota Influences Our Immune System

How The Gut Microbiota Influences Our Immune System

The gut microbiota influences many aspects of human physiology, from metabolism, to the cardiovascular system or the nervous system, for example. In this article, we focus on the interaction between the gut microbiota and our immune system.

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Hormesis: Benefits of Training Your Stress Response

Hormesis: Benefits of Training Your Stress Response

On the Collective Insights podcast, Dr. Aubrey de Grey, Dr. Dan Pardi, Daniel Schmachtenberger, and Dr. Dan Stickler share their insights on the difference between beneficial and damaging stress. We answer "What is hormesis?" and "How can we effectively manage stress?" Read on to understand how certain kinds of stress actually benefit the body, and which ones to avoid. 

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Why Algae is a Powerful Longevity and Detox Hack - A Q+A With the Founder of ENERGYbits

Why Algae is a Powerful Longevity and Detox Hack - A Q+A With the Founder of ENERGYbits

As Neurohackers, longevity, in relation to both lifespan and healthspan, is a topic of great interest to us. Scientific understanding in these areas is advancing rapidly as are studies linking algae to longevity.

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How is NAD+ Made? Salvage Pathway

How is NAD+ Made? Salvage Pathway

The salvage pathway is used to produce NAD+ from nicotinamide molecules. Whether the source of the nicotinamide is vitamin B3 (as niacinamide), newer nicotinamides (e.g., nicotinamide riboside [NR], nicotinamide mononucleotide [NMN]), or molecules in food that get broken down during digestion into nicotinamide, the salvage pathway turns them into NAD+ in our tissues.

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How is NAD+ Made? De Novo Synthesis

How is NAD+ Made? De Novo Synthesis

Most organisms have several alternatives for producing the NAD+ molecule. In humans, there are three major NAD+ biosynthesis pathways: the De Novo Pathway, starting from the essential amino acid L-tryptophan; the Preiss-Handler pathway, using niacin (nicotinic acid); and the Salvage Pathway from niacinamide (nicotinamide). In this article, we’ll be covering the De Novo Pathway.

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Mitochondria: Exploring 5 Lifestyle Habits to Benefit Cell Health

Mitochondria: Exploring 5 Lifestyle Habits to Benefit Cell Health

Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. In this article, we explore lifestyle habits that improve mitochondrial health and support healthy aging.

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Antiviral Immunity: Understanding Viruses and How the Immune System Responds to Viral Infections

Antiviral Immunity: Understanding Viruses and How the Immune System Responds to Viral Infections

Viruses are everywhere cellular life is present, often in unfathomable numbers. They mutate very often, frequently by recombining with other viruses. This means that new viruses are constantly being generated.

As we’ll learn in this article, viruses are very simple, but despite their simplicity, they are very effective and impressive little creatures. We’ll also learn how our immune system rises to the challenge.   

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How Does The Immune System Work? Part 2: The Adaptive Immune System

How Does The Immune System Work? Part 2: The Adaptive Immune System

The adaptive immune system is responsible for the more complex and optimized immune responses that develop when innate immunity is insufficient to manage a threat. It is the specific immunity we acquire over time as the immune system is challenged with new antigens and learns to deal with them.

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What Is The Citric Acid Cycle?

What Is The Citric Acid Cycle?

The citric acid cycle, also known as the Krebs cycle or tricarboxylic acid (TCA) cycle, is a circular loop rotating through eight organic acid intermediates (e.g., citrate, malate, oxaloacetate). This cycle plays a critical role in moving cell energy production forward, because it is the first pathway of the final stage of energy extraction from nutrients, in which carbon units are fully oxidized. The intermediate products formed in this cycle are also used to build molecules including proteins, DNA, and RNA.

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Qualia Life: Putting the Healthy Aging Puzzle Together

Qualia Life: Putting the Healthy Aging Puzzle Together

We all age. But, we don’t all age at the same rate. From a bottom-up point of view, we are a complex colony of tens of trillions of individual cells. We care about what healthier cells allows the body to do better. Qualia Life is our solution to cell support for better aging. 

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Neglected Areas of Research: What Study Would You Have Done with Unlimited Resources?

Neglected Areas of Research: What Study Would You Have Done with Unlimited Resources?

To improve our healthcare we need important research that is not being done. Often times health topics aren't studied due to lack of funds and resources. We’ve been asking our podcast guests where the missing research is in the field they are experts in. Read on to find out what they said.

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Mitohormesis: How Mitochondria Protect Themselves from Oxidative Stress

Mitohormesis: How Mitochondria Protect Themselves from Oxidative Stress

In this article, we’re going to learn about mitohormesis, the activity of reactive oxygen species (ROS) as signaling molecules, and how and why ROS can be both beneficial and harmful. We will also discuss what leads to excessive ROS production and accumulation, how this associates with aging, and where antioxidants fit into the equation. Lastly, we’ll discuss nutritional strategies that can support the antioxidant defenses cells and mitochondria use to protect themselves against excessive ROS.

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