This study aimed to assess whether Qualia Skin, by providing skin nourishment from within and supporting comprehensive skin health and healthy skin aging, would change participant satisfaction and self-ratings of aspects of the skin’s feel and appearance.

Understanding the main aspects of skin health, the major processes and pathways of healthy skin physiology, and the mechanisms of skin aging is essential to learning how to keep the skin healthy and youthful.

The best way to understand how to keep the skin healthy and youthful is by understanding what are the factors that impact skin health and aging, which is what we’ll explore in this article.

The skin is a special organ that combines the body’s major systems: circulatory, nervous, muscular, immune, endocrine. It is a barrier that protects us against the threats in our environment, but it is also a sensory organ that allows us to perceive the outside world. Read on to understand both the structure and function of the skin.

Immunometabolism is the crosstalk between metabolic and immunological processes. Mitochondria, the cellular structures that generate cell energy, are key elements in the crosstalk between metabolic and immune signaling pathways. 

Oxidative phosphorylation (OXPHOS) is the major pathway of ATP production. ATP is the energy-rich molecule that powers cellular processes that require energy input. OXPHOS occurs in mitochondria and uses energy extracted in the metabolism of cellular fuels, particularly in glycolysis, fatty acid oxidation, and the citric acid cycle, to power the production of ATP.

We invited the biohacking pioneer, Dave Asprey, to talk about the science backed practices to age better and live longer. He shares with us his favorite biohacks to improve your gut bacteria, your heart rate variability, your mitochondrial function and more. There is not just 1 thing that causes aging, but 7 functions that contribute to the aging process.

There is so much advice on longevity and aging that it can be hard to sort through all of the information. In this podcast transcript we dive into the science-backed approaches for living a longer and healthier life. Valter Longo, Ph.D., has thirty years of experience in longevity and healthy eating, and is one of the world’s experts in the field.

In 1958, Jack Preiss and Philip Handler published a scientific paper describing how NAD⁺ was made from niacin in three steps.(1) This pathway was later named the Preiss-Handler pathway after the co-discoverers. It describes the enzyme steps needed to convert niacin into the NAD⁺ molecule.

BioVin® is a premium quality grape extract made from the juice, seeds, and skins of red grapes grown in France. It's rich in both trans-resveratrol and grape polyphenols.

The salvage pathway is used to produce NAD⁺ from nicotinamide molecules. Whether the source of the nicotinamide is vitamin B3 (as niacinamide), newer nicotinamides (e.g., nicotinamide riboside [NR], nicotinamide mononucleotide [NMN]), or molecules in food that get broken down during digestion into nicotinamide, the salvage pathway turns them into NAD⁺ in our tissues.

Most organisms have several alternatives for producing the NAD⁺ molecule. In humans, there are three major NAD⁺ biosynthesis pathways: the De Novo Pathway, starting from the essential amino acid L-tryptophan; the Preiss-Handler pathway, using niacin (nicotinic acid); and the Salvage Pathway from niacinamide (nicotinamide). In this article, we’ll be covering the De Novo Pathway.

Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. In this article, we explore lifestyle habits that improve mitochondrial health and support healthy aging.

Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. Here we explore temperature and light therapy to improve mitochondrial health and support healthy aging.

In this article we’ll be covering the “big picture” when it comes to NAD. We’ll be doing a deeper dive on specific topics we introduce in this article in subsequent articles in this series. As you go through this series of articles please keep in mind that, like other molecules in the body, NAD⁺ is a means to an end. We don’t care about NAD⁺ on its own; we care about it because of what it allows cells to do. 

In Silicon Valley, the hub of anti-aging research and funding, countless entrepreneurs and high-profile celebrities use fasting to combat the effects of aging. In Anti-Aging Benefits of Fasting, we will explore the mechanisms that create these fasting benefits. This part is more scientific than the others, but we emphasize only crucial components in an easily digestible format.