Qualia Night was designed to support the body’s natural shift from daytime function, a period characterized by activity, into the rest, repair, and rejuvenation functions that dominate the night. One of the goals of the product is to promote a feeling of calmness and relaxation in the evening. Another goal is to support sounder sleep. A third goal is to have users wake feeling refreshed and restored. And the last goal is for users to have a next-day nootropic experience, with what they took at night supporting performance in areas such as productivity, energy, and stress the following day.*
A randomized double-blind placebo-controlled crossover study on otherwise healthy adults with poor sleep quality (i.e., occasional sleeplessness) was conducted to examine Qualia Night supplementation on sleep quality and health outcomes. The outcomes measured were sleep quality, restorative sleep, health-related quality of life, perceived stress, mood, daytime fatigue, cognitive function, and product usability/likability.
Participants were 25 male (n = 11) and female (n = 14) adults (M age = 40.14, SD = 7.72, age range = 25 to 50 years) with poor sleep quality. Most of the participants were White (n = 21), followed by Mixed Caucasian/Hispanic/Latino (n = 1), Mixed Caucasian/Asian/Asian American (n = 1), Black/African American (n = 1), and Hispanic/Latino (n = 1). All the participants reported poor sleep quality as determined by the Insomnia Severity Index (i.e., score of 8 or greater on the index).
|Randomized Placebo-Controlled Crossover Trial||Double-blind||
1. Night (4 caps/day)
2. Placebo (4 caps/day
Participants who met the inclusion criteria (based on responses to the Prescreen Survey) were contacted to discuss the intervention. Interested participants signed an Institutional Review Board Approved Informed Consent (Sterling IRB) and then Qualia Night and placebo were delivered to their home address.
Participants were instructed to take four capsules 3 to 4 hours prior to nighttime sleep for 5 days each week (self-selected days). Each evening at 6:00 pm a text reminder was sent to all participants to take the capsules 3 to 4 hours before bed. Each morning the participants were sent a Daily Diary to complete that assessed their supplement adherence, adverse events, sleep quality, and mood. As well, the participants completed assessments of their sleep quality, productivity, executive functioning (i.e., cognition), perceived stress, mood, daytime fatigue, and health-related quality of life at Baseline, following talking Qualia Night, and following taking a placebo.
A total of 25 adults provided informed consent and were enrolled in the study. All 25 participants completed the study, representing an adherence rate of 100%.
The Qualia Night group showed an improvement vs. baseline in all areas assessed. Improvements, as compared with placebo, were shown in restorative sleep, productivity, vigor, perceived stress, and self-assessed general health, although the improvements vs. placebo were not statistically significant (p>0.05). The participants showed the largest percent improvement vs. baseline in the areas of sleep quality, stress reduction, productivity, energy levels, and general mental health related quality of life measures.* These differences were statistically significant (p<0.05).
While Neurohacker Collective is encouraged by the results of this study, additional studies are required to more definitively document the benefits of supplementation with Qualia Night.
Demographic Information (Baseline only):
The following demographic items were assessed: age, gender, profession, ethnicity, physical and mental health status, and sleep quality.
Main Outcome Measures:
The following measures were completed at Baseline, following supplementation with Qualia Mind, and following supplementation with a placebo.