Huperzine A

Huperzine A is a potent natural synaptic enzyme modulator. Studies indicate its ability to support learning, memory, neuroplasticity, and executive function.

Scientific Name:
Huperzine A extracted  from Huperzia serrata

  • Acetylcholinesterase inhibitor[1]
  • NMDA receptor antagonist[1]
  • Neuroprotective against hydrogen peroxide damage, glutamate excitotoxicity, and beta amyloid pigmentation[1]
  • Neurogenic through increased proliferation of hippocampal neural stem cells and NGF stimulation[2]
  • Upregulates REM sleep (many report increased lucid dreaming)
  • Supports memory consolidation and neuroplasticity[1]
  • Synergistic with cholinomimetics and cholinosensitizers

[1] Wang R, et al (2006). Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine. Acta Pharmacol Sin, 27(1):1-26. doi: 10.1111/j.1745-7254.2006.00255.x
[2] Ma T, et al (2013). Huperzine A promotes hippocampal neurogenesis in vitro and in vivo. Brain Res, 1506:35-43. doi: