DL-Phenylalanine
Overview:
DLPA is a mixture of two forms of the essential amino acid phenylalanine, the naturally occurring L-phenylalanine and the synthetic D-phenylalanine with nootropic effects. DLPA enhances mood and can increases alertness and improve memory and learning.
Scientific Name:
DL-Phenylalanine
Mechanisms:
- DL-Phenylalanine crosses the blood-brain barrier easily
- Increases the production of dopamine and noradrenalin – mood enhancer
- Decreases chronic pain by blocking the action of enkephalinase[1]
- Binds to Glutamate AMPA receptors improving synaptic communication –memory and learning enhancement[2]
REFERENCES
[1] Russell AL & McCarty MF (2000). DL-phenylalanine markedly potentiates opiate analgesia – an example of nutrient/pharmaceutical up-regulation of the endogenous analgesia system. Med Hypotheses, 55(4):283-8. doi: 10.1054/mehy.1999.1031
[2] Hill RA, et al (1997). Structure–activity studies for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid receptors: acidic hydroxyphenylalanines. J Med Chem, 40(20):3182-91. doi: 10.1021/jm950028z