Collective Insights Blog

Transcript: Valter Longo Interview on the Science of Longevity

Transcript: Valter Longo Interview on the Science of Longevity

There is so much advice on longevity and aging that it can be hard to sort through all of the information. In this podcast transcript we dive into the science-backed approaches for living a longer and healthier life. Valter Longo, Ph.D., has thirty years of experience in longevity and healthy eating, and is one of the world’s experts in the field.

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Mitohormesis: How Mitochondria Protect Themselves from Oxidative Stress

Mitohormesis: How Mitochondria Protect Themselves from Oxidative Stress

In this article, we’re going to learn about mitohormesis, the activity of reactive oxygen species (ROS) as signaling molecules, and how and why ROS can be both beneficial and harmful. We will also discuss what leads to excessive ROS production and accumulation, how this associates with aging, and where antioxidants fit into the equation. Lastly, we’ll discuss nutritional strategies that can support the antioxidant defenses cells and mitochondria use to protect themselves against excessive ROS.

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What is Mitochondrial Biogenesis? Benefits & Effects

What is Mitochondrial Biogenesis? Benefits & Effects

Similar to many other cellular processes, the creation of new mitochondria (a process called mitochondrial biogenesis), and the interacting pathways that influence it, suffers with aging. This is the bad news. The good news is that there are things we can do to better support maintaining a fitter mitochondrial network.

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What is CD38? An Exploration of NAD+ Consumption Uses and Functions of CD38

What is CD38? An Exploration of NAD+ Consumption Uses and Functions of CD38

In this article, we’re going to introduce an indirect way of supporting NAD+. Rather than making more, this article will be teaching you about using less. Using less requires downregulating a protein called cluster of differentiation 38 (CD38 for short). When CD38 is not as active, less NAD+ is used by it. The result is higher NAD+ levels and greater NAD+ availability for important healthy aging uses.

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NAD+ Consumption Uses: An Overview

NAD+ Consumption Uses: An Overview

Key Learning Objectives

  • Learn why NAD+ is said to be “consumed” when used for signaling.
  • Introduce the 3 main NAD+ “consumers.”
  • Find out why overconsumption of NAD+ by one consumer leaves less for others.
  • Discover how consumption uses change with aging.

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Benefits of Gynostemma pentaphyllum Whole Herb Extract

Benefits of Gynostemma pentaphyllum Whole Herb Extract

Gynostemma pentaphyllum (Southern Ginseng) is an herb attributed with having ginseng status. Until fairly recently Gynostemma pentaphyllum was used primarily in mountainous regions of southern China and northern Vietnam. It’s been described as the "immortality herb,” because people within Guizhou Province, where herbal teas made from the plant are consumed regularly, are said to have a history of unusual longevity. 

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Sophorae japonica L. Flower Extract: Sources and Benefits

Sophorae japonica L. Flower Extract: Sources and Benefits

Rutin is a type of polyphenol called a flavonoid glycoside. It’s composed of quercetin and the disaccharide rutinose. It’s also called rutoside, quercetin-3-O-rutinoside and sophorin. While it’s found in a wide variety of plants, including citrus, foods with the highest concentrations of rutin include capers, black olives, buckwheat, and asparagus. The most common use of rutin has been for supporting healthy veins. But it does much more.

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Ashwagandha: Sources and Benefits

Ashwagandha: Sources and Benefits

Ashwagandha is an Ayurvedic herb often referred to as “Indian ginseng.” Within this system of it was classified as a general tonic and strength promoting. Its uses included infusing energy and vigor in circumstances characterized by exhaustion or a lack of physical energy. 

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Mitochondria: Exploring 5 Lifestyle Habits to Benefit Cell Health

Mitochondria: Exploring 5 Lifestyle Habits to Benefit Cell Health

Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. In this article, we explore lifestyle habits that improve mitochondrial health and support healthy aging.

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Mitochondria Health: An Exploration of Temperature and Light Therapy

Mitochondria Health: An Exploration of Temperature and Light Therapy

Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. Here we explore temperature and light therapy to improve mitochondrial health and support healthy aging.

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Anti-Aging Benefits of Intermittent Fasting

Anti-Aging Benefits of Intermittent Fasting

In Silicon Valley, the hub of anti-aging research and funding, countless entrepreneurs and high-profile celebrities use fasting to combat the effects of aging. In Anti-Aging Benefits of Fasting, we will explore the mechanisms that create these fasting benefits. This part is more scientific than the others, but we emphasize only crucial components in an easily digestible format.

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